Michael R. Sperling, MD
Baldwin Keyes Professor of Neurology
Vice Chair, Neurology Research
Division Chief for Epilepsy
Director, Jefferson Comprehensive Epilepsy Center
Director, Clinical Neurophysiology Laboratory
Associate Director, Epilepsy & Clinical Neurophysiology Fellowship Programs
Contact
901 Walnut Street
Suite 400
Philadelphia, PA 19107
215-955-1222
215-955-0606 fax
Michael R. Sperling, MD
Baldwin Keyes Professor of Neurology
Vice Chair, Neurology Research
Division Chief for Epilepsy
Director, Jefferson Comprehensive Epilepsy Center
Director, Clinical Neurophysiology Laboratory
Associate Director, Epilepsy & Clinical Neurophysiology Fellowship Programs
Education
Medical School
Temple University School of Medicine
Residency
Mount Sinai Medical Center
Fellowship
UCLA Medical Center
Publications
- Association of Normative and Non-Normative Brain Networks With Cognitive Function in Patients With Temporal Lobe Epilepsy
- Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes
- To plan efficacious epilepsy surgery
- Farewell from the Editor-in-Chief
- An interview with Marwa Elamin, 2024 Epilepsia prize winner for basic science research
Board Certifications
- American Board of Psychiatry and Neurology
- American Board of Clinical Neurophysiology
- American Board of Psychiatry and Neurology, Epilepsy
Hospital Appointment
Thomas Jefferson University Hospital, Philadelphia, PA
- Director, Jefferson Comprehensive Epilepsy Center, 1997 - present
- Director, Clinical Neurophysiology Laboratory, 1997 - present
Graduate Hospital, Philadelphia, PA
- Director, Neurophysiology Laboratory, 1985 - 1997
- Director, Epilepsy Monitoring Unit 1985 - 1997
- Director, Comprehensive Epilepsy Center, 1995- 1997
Research & Clinical Interests
- Surgical treatment of epilepsy: outcome after surgery, predictors of surgical outcome, neurobehavioral effects of surgery;
- Mortality in epilepsy: research examining features associated with increased mortality in patients with epilepsy;
- Electrophysiology of epilepsy: studies of EEG in epilepsy, intracranial EEG in epilepsy examining features related to seizure control, seizure propagation and spread;
- Genetics of epilepsy: project examining genetic factors predisposing to heightened susceptibility for epilepsy;
- Electrophysiology of cognition;
- Investigational therapeutics in epilepsy: participation in multiple studies of new pharmaceuticals and devices to treat epilepsy.
PROFESSIONAL ACTIVITIES
- Editor-in-Chief, Epilepsia (the journal of the International League Against Epilepsy)
- Fellow, American Epilepsy Society
- Fellow, American Academic of Neurology
- Member, American Clinical Neurophysiology Society; past president
- Member, Philadelphia Neurological Society; past president
- Member, Publication Committee and Finance Committee of the International League Against Epilepsy
- Member, American Epilepsy Society Guideline Panel
- Board member, Epilepsy Foundation of Eastern Pennsylvania
- Organizer and lecturer at national and international Neurology and Epilepsy meetings
Educational Activities
- Teaching medical students, residents and fellows.
- Regular instructor at resident and fellow epilepsy/neurophysiology conferences.
- Regular instructor at resident neurology conference.
Clinical Activities
- Developed Epilepsy Program at the Graduate Hospital, including design and development of the epilepsy monitoring unit and EEG laboratory, epilepsy surgical program (with Dr. Michael O'Connor), contributing to development of experimental antiepileptic drug program, and clinical research program.
- Developed the Comprehensive Epilepsy Center at Thomas Jefferson University, including designing and developing the epilepsy monitoring unit and EEG laboratory, epilepsy surgical program (with Dr. Michael O'Connor), experimental antiepileptic drug program, and clinical research program.
- Developed Intraoperative Brain Mapping Program at Thomas Jefferson University Hospital
Editorial Positions
- Editor-in-Chief, Epilepsia, 2014 – present
- Associate Editor: Epilepsia 2007 - 2014
- Epilepsy Research, 1999-2007
- Epilepsy Advances, 1993-95, 1996-1998
- Member - Editorial Board: Journal of Epilepsy, 1991-1999
- Reviewer: Electroencephalography and Clinical Neurophysiology, Annals of Neurology, Neurology, Epilepsia, Journal of Clinical Neurophysiology, Neuroradiology, Journal of Neurological Sciences, Archives of Neurology, JAMA, New England Journal of Medicine, Lancet