Gudrun Debes, DVM
Associate Professor
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Gudrun Debes, DVM
Associate Professor
Education
Medical School
DVM, Charité University Medicine, Free University Berlin, Berlin, Germany - 2002
Fellowship
Stanford University School of Medicine, Stanford, CA
Most Recent Peer-Reviewed Publications
- Secreted IgM modulates IL-10 expression in B cells
- The Lack of Natural IgM Increases Susceptibility and Impairs Anti-Vi Polysaccharide IgG Responses in a Mouse Model of Typhoid
- Immunoregulation by antibody secreting cells in inflammation, infection, and cancer
- Skin-Homing Regulatory B Cells Required for Suppression of Cutaneous Inflammation
- Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species
Fellowship
Stanford University School of Medicine, Stanford, CA
Research & Clinical Interests
My laboratory seeks to understand the regulation of T and B cell recirculation through and function within nonlymphoid tissues with a main focus on the skin and the respiratory tract. We aim to discover novel approaches to manipulate lymphocytic tissue infiltrates with the goal to moderate inflammation in inflammatory and autoimmune diseases and to enhance organ-specific immunity in infection and cancer.
My laboratory has three main interests:
(1) The migration of pro and anti-inflammatory effector/memory T and B cell subsets from blood into tissues in inflammation and infection. (2) The mechanisms of lymphocyte egress from nonlymphoid tissues via afferent lymph vessels and the role of this process in local inflammation and immunity. (3) The migration and function of skin-homing B cells and NK cells, which are lymphocyte subsets that are traditionally not associated with skin immune responses.