mitochondria; skeletal muscle; liver; heart; substrate metabolism; regulation of fatty acid metabolism by mitochondrial thioesterases and associated mouse models; human mutations in the mitochondrial phosphate carrier and associated cellular models.
Erin L. Seifert, PhD
Associate Professor
Contact Information
Associate Professor
Research Interests
Education
Education
PhD, McGill University, Montreal, Canada (2002)
Fellowship
McGill University and University of Ottawa, Ottawa, Canada
Most Recent Peer-Reviewed Publications
- PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival
- Mammalian mitochondrial inorganic polyphosphate (polyP) and cell signaling: Crosstalk between PolyP and the activity of AMPK
- Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology
- MICU1 and MICU2 control mitochondrial calcium signaling in the mammalian heart
- Adaptation of the heart to frataxin depletion: evidence that integrated stress response can predominate over mTORC1 activation
Professional Societies
Biophysical Society, United Mitochondrial Disease Foundation
Academic Interests
Research (see below), teaching (cellular energy transformation; mitochondria; substrate metabolism; redox biology)