A new study by Thomas Jefferson University neuroscientist Jay Schneider, PhD, suggests that the toxic effects of lead can be mitigated by attentive maternal care and an enriched environment in an animal model.

Silva Markovic-Plese, MD, PhD and her team at Thomas Jefferson University have been studying RRMS for more than a decade. In a previous study, they noticed elevated levels of an immune chemical called, IL-11, in the cerebrospinal fluid surrounding the brain and spinal cord of RRMS patients. They wanted to explore why.

In a new paper, published in EMBO Reports, a team including Davide Trotti, PhD, a neuroscientist at Thomas Jefferson University, showed how altered glucose metabolism in the brain and spinal cord are damaging to motor neurons in preclinical models that carry the genetic C9-NRE mutation. 

In a recent study, Scott A. Waldman, MD, PhD, and his team discovered that a gut receptor protein called GUCY2C could prevent PD development by protecting against brain damage and toxic insult.

Neuroscientist Manuel Covarrubias, MD, PhD and his research assistant Qiansheng Liang, MD led a study published in Nature Communications that focused on Kv3 channels, the subclass of voltage-gated potassium channels that selectively bind AUT5. 

A single patient will help researchers learn if brain implants connected to a robotic brace can help stroke patients overcome abnormal movement and restore abilities.