Tonio Pera, PhD

Assistant Professor of Medicine, Division of Pulmonary, Allergy & Critical Care Medicine

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Contact

1020 Locust Street
Jefferson Alumni Hall, Room 236
Philadelphia, PA 19107

Email Tonio Pera

215-503-5127
215-503-5731 fax

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Tonio Pera, PhD

Assistant Professor of Medicine, Division of Pulmonary, Allergy & Critical Care Medicine

Research & Clinical Interests

The Pera lab focuses on studying how GPCR signaling and functions are regulated by arrestins and GPCR kinases (GRKs), primarily in airway smooth muscle. In particular, we are interested in how muscarinic receptor biased signaling affects airway physiology. Biased signaling refers to the ability of GPCRs to induce disparate signaling pathways when bound to certain (biased) ligands. Biased signaling is often regulated by arrestins and GRKs. Muscrinic receptors are major drivers of airway pathology and therefore understanding muscarinic biased signaling is crucial for delineating signaling pathways which drive lung disease, as well as provide novel targets for therapy.

Education

PhD, University of Groningen in the Netherlands 2011

Publications

 

 

Professional Societies

  • American Thoracic Society