Steven E. McKenzie, MD, PhD
Professor of Medicine
Cardeza Foundation for Hematologic Research
Contact
1020 Locust Street
Suite 394
Philadelphia, PA 19107
215-955-8544
215-955-9170 fax
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Steven E. McKenzie, MD, PhD
Professor of Medicine
Cardeza Foundation for Hematologic Research
Publications
- A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity
- Plasma growth factors maintain constitutive translation in platelets to regulate reactivity and thrombotic potential
- Diagnostic value of antibody-induced procoagulant platelets in heparin-induced thrombocytopenia: communication from the ISTH SSC Subcommittee on Platelet Immunology
- Aspirin pharmacokinetics and pharmacodynamics through gestation
- The Function of ASK1 in Sepsis and Stress-Induced Disorders
Research & Clinical Interests
Dr. McKenzie directs two major research projects. The first project involves vascular biology, with a focus on immune-mediated thrombocytopenia and thrombosis syndromes. This work, done in collaboration with Dr. Michael Reilly, led to the first model of heparin-induced thrombocytopenia and thrombosis. New work on effects of elevated cholesterol and athrosclerosis on HITT, and on microparticles and tissue factor, is ongoing.