James S. Schwaber, PhD
Daniel B. Baugh Professor in Anatomy & Director of the Daniel B. Baugh Institute, Department of Pathology & Genomic Medicine
Contact Information
1020 Locust Street
Jefferson Alumni Hall, Suite 381
Philadelphia, PA 19107
Daniel B. Baugh Professor in Anatomy & Director of the Daniel B. Baugh Institute, Department of Pathology & Genomic Medicine
Research and Clinical Interests
Dr. Schwaber uses systems biology approaches in mammalian brain to study adaptive neuronal processes. Specifically his interests involve mechanisms by which hypertension arises in homeostatic cardiorespiratory regulatory circuits, by which the symptoms of alcohol withdrawal are produced and by which phase shifting of light causes the brain's master clock to reorganize circadian behavior.
Education
PhD, University of Miami - 1973
Publications
- Unpacking the multimodal, multi-scale data of the fast and slow lanes of the cardiac vagus through computational modelling
- Multi-organ gene expression analysis and network modeling reveal regulatory control cascades during the development of hypertension in female spontaneously hypertensive rat
- Neuromodulatory co-expression in cardiac vagal motor neurons of the dorsal motor nucleus of the vagus
- Dynamic dysregulation of transcriptomic networks in brainstem autonomic nuclei during hypertension development in the female spontaneously hypertensive rat
- Closed-loop modeling of central and intrinsic cardiac nervous system circuits underlying cardiovascular control
Other Professional Appointments
Adjunct Professor Chemical Engineering, University of Delaware