John Milligan, PhD
Assistant Professor
Contact
John Milligan, PhD
Assistant Professor
Research & Clinical Interests
Our group focuses on developing new chemical reactions that are driven by blue LED light. These studies are within the broader “photoredox” subfield of organic chemistry, which is a powerful paradigm for building organic molecules in a mild and expedient fashion. Our specific interest within this theme is the development of novel radical/polar crossover reactions to create heterocycles from nitrogen-containing unsaturated substrates. Other ongoing research involves an intramural collaboration with design experts at Jefferson to develop 3D printed devices that are useful for organic chemistry.
Education
Postdoctoral Scholar, University of Pennsylvania, Philadelphia, PA, 2019
PhD - University of Pittsburgh, Pittsburgh, PA, 2018
BS - Allegheny College, Meadville, PA, 2012
Publications
- Green Oxidation of Aromatic Hydrazide Derivatives Using an Oxoammonium Salt
- 3-Chloropropylbis(catecholato)silicate as a Bifunctional Reagent for the One-Pot Synthesis of Tetrahydroquinolines from o-Bromosulfonamides
- Hydrozirconation of alkynes
- A Practical Oxidation Experiment for Undergraduate Students: Bobbitt's Salt as a "green" Alternative
- Bicyclobutanes: from curiosities to versatile reagents and covalent warheads
- What Is the Value of Synchronous Engagement in Small Remote Organic Chemistry Classes? Analysis of Multiple-Choice Polling Data from the COVID-Impacted Spring Semester of 2020
- Radical-Polar Crossover Annulation: A Platform for Accessing Polycyclic Cyclopropanes
- Alkyl-C-C-Bindungsbildung durch Nickel/Photoredox-Kreuzkupplung
- Alkyl Carbon–Carbon Bond Formation by Nickel/Photoredox Cross-Coupling
- Photoredox Radical/Polar Crossover Enables Construction of Saturated Nitrogen Heterocycles
- Radical/Polar Annulation Reactions (RPARs) Enable the Modular Construction of Cyclopropanes
- Development of an undergraduate course in chemical laboratory safety through an academic/industrial collaboration
- Hydrophosphination of Bicyclo[1.1.0]butane-1-carbonitriles
- Click chemistry: Straining to react
- Synthesis of phosphaguanidines by hydrophosphination of carbodiimides with phosphine boranes