Renato V. Iozzo, MD
Gonzalo E. Aponte Professor, Pathology, Anatomy, & Cell Biology
Deputy Chair, Pathology, Anatomy & Cell Biology
Professor, Biochemistry & Molecular Biology
Director, Electron Microscopy
Contact Information
1020 Locust Street
336 Alumni Hall
Philadelphia, PA 19107
215-503-2208
215-923-7969 fax
Gonzalo E. Aponte Professor, Pathology, Anatomy, & Cell Biology
Deputy Chair, Pathology, Anatomy & Cell Biology
Professor, Biochemistry & Molecular Biology
Director, Electron Microscopy
Research and Clinical Interests
Professor of Pathology and Cell Biology, and Director of the Extracellular Matrix Program at the Kimmel Cancer Center, Thomas Jefferson University. After receiving an M.D. degree summa cum laude from the University of Florence, Italy, he moved to the Department of Pathology at the University of Washington, where he completed a five-year Residency/Fellowship. Following a six-year faculty appointment at the University of Pennsylvania, he moved to Thomas Jefferson University. Dr. Iozzo has received many awards including the Benjamin Castleman Award from the International Academy of Pathology, the Junior Faculty Research Award from the American Cancer Society, the Burlington Resources Foundation Faculty Achievement Award, and the Faculty Research Award from the American Cancer Society. In 2008, Dr. Iozzo received an Honorary Professorship at the School of Life Sciences, University of Manchester, UK. His research focuses on the biology of proteoglycans and their roles in cancer and angiogenesis.
Publications
- Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer progression
- A role for decorin in improving motor deficits after traumatic brain injury
- Global impact of proteoglycan science on human diseases
- Emilin2 fosters vascular stability by promoting pericyte recruitment
- Progranulin and EGFR modulate receptor-like tyrosine kinase sorting and stability in mesothelioma cells
Medical School
MD, Florence, University of Florence School of Medicine (Summa Cum Laude ), Italy
Medical Licensure (Active), Commonwealth of Pennsylvania
Medical Licensure (Active), Washington State
Residency
Anatomic Pathology Residency, University of Washington, Seattle WA
Fellowship
NIH Post-Doctoral Fellowship, University of Washington, Seattle WA
Board Certification
Board Certification, American Board of Pathology
Other Expertise
ACADEMIC COMMITTEES
At University of Pennsylvania
1983-1988 Member, Service Center Review Committee
1985-1988 Member, Medical School Admission Committee
1988 Member, Committee for Reviewing Cardiovascular Teaching
At Thomas Jefferson University
1989-1999 Member, Admission Committee for Gibbon Scholar, M.D./PhD Program
1989-2000 Member, Career Planning Program Committee, Department of Pathology
1991-present Member, Kimmel Cancer Institute
1991-2001 Member, Pathology Residency Review Committee, Department of Pathology
1993-1997 Member, Committee on Research, Jefferson Medical College
1994-1997 Chairman, Subcommittee on Award Nomination, Committee on Research
1995-2005 Member, Curriculum Committee, Department of Pathology
1996-1999 Advisory Committee of the Professorial Faculty, Jefferson Medical College
2002-2006 Member, Committee on Students Affairs, Thomas Jefferson University
2005-2006 Member, Cancer Biology Strategic Plan Committee, Kimmel cancer Center
2005-2006 Member, Bone and Matrix Biology Strategic Plan Committee, Thomas Jefferson University
2009- Member Executive Committee, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University
2010- Member, Executive Committee, Kimmel Cancer Center, Thomas Jefferson University
INVITED LECTURES AND SYMPOSIA (SELECTED since 2005)
2005 Invited Speaker, University of Delaware, Wilmington, DE
2005 Invited Speaker, Symposium in honor of Robert Rosenberg, MIT, Boston
2005 Chair and Speaker, Symposium on Extracellular Matrix Regulation of Angiogenesis Co-sponsored by ASIP and ASMB, Experimental Biology Meeting, San Diego, CA
2005 Invited Speaker, International Symposium on Proteoglycans in Signaling, Stockholm, Sweden
2005 Visiting Professor, Medical College of Wisconsin, Milwaukee, WI
2005 Invited Speaker, 13th Symposium on Glycosaminoglycans, Lake Como, Italy
2005 Invited Speaker, 18th International Symposium on Glycoconjugates, Florence, Italy
2005 Co-organizer and Session Chair, 12th International Symposium on Basement Membranes, Philadelphia, PA
2005 Visiting Professor, Darthmouth Medical School, Hannover, NH
2005 Visiting Professor, Boston University Medical School, Boston, MA
2005 Visiting Professor, Vanderbilt University Medical Center, Nashville, TN
2006 Visiting Professor, Case Western Reserve University School of Medicine, Cleveland, OH
2006 Visiting Professor, University of Alabama, Birmingham, AL
2006 Visiting Professor, McGill University, Montreal, Canada
2006 Session Chair and Speaker, International Symposium on Extracellular Glycomatrix in Health and Disease, Awaji, Japan
2006 Session Chair/Speaker, Gordon Research Conference on Basement Membranes, Il Ciocco, Italy
2006 Session Chair and Speaker, Gordon Research Conference on Proteoglycans, Proctor Academy, NH
2006 Invited Speaker, Priority Research Program on Basement Membranes, Freiburg, Germany
2006 Session Chair, 3rd annual meeting, American Society for Matrix Biology, Nashville, TN
2007 Visiting Professor, Harvard School of Dental Medicine, Boston, MA
2007 Visiting Professor, University of Alabama at Birmingham, AL
2007 Session Chair, International Conference on Proteoglycans, Rio De Janeiro, Brazil
2007 Invited speaker, Pan-Pacific Connective Tissue Society Meeting, Cairns, Australia
2008 Invited Speaker, Gordon Research Conference on Basement Membranes, Bidderford, ME
2008 Session Chair, Gordon Research Conference on Proteoglycans, Proctor Academy, NH
2008 Invited Speaker, International Conference of Cell Biology, Seoul, South Korea
2008 Chair, Biennial Meeting of the American Society for Matrix Biology, San Diego, CA
2009 Keynote Speaker, Hellenic Society for Matrix Biology, Patras, Greece
2009 Plenary Speaker, FEBS Advance Lecture Course on Matrix Pathobiology, Patras, Greece
2009 Invited Speaker, 6th International Conference on Proteoglycans, Aix les Bains, France
2009 Invited Speaker, Klenk Symposium on Molecular Medicine, Cologne, Germany
2009 Invited Speaker, Annual Meeting of the Society for Glycobiology, San Diego, CA
2010 Visiting Professor, University of Pennsylvania, Philadelphia, PA
2010 Visiting Professor, University of Pittsburgh, Pittsburgh, PA
2010 Keynote Speaker, German and British Society for Matrix Biology, Frankfurt, Germany
2010 Visiting Professor, University of Georgia, Athens, GA
2010 Plenary Speaker and Session Chair, XXII FECTS Meeting, Davos, Switzerland
2010 Visiting Professor, University of Zurich, Zurich, Switzerland
2010 Session Chair and Member of the Organizing Committee, Gordon Research Conference on Proteoglycans, Proctor Academy, NH
2010 Session Chair and Member of the Organizing Committee, Biennial Meeting of the American Society for Matrix Biology, Charleston, SC
2010 Visiting Professor, Washington University, St. Louis, MO
2010 Visiting Professor, Harvard School of Dental Medicine, Boston, MA
2010 Visiting Professor, University of Florence school of Medicine, Florence, Italy
2011 Invited Speaker, Symposium in honor of Bjorn Olsen, Harvard Medical School, Boston, MA
2011 Plenary Speaker, FEBS Advance Lecture Course on Matrix Pathobiology, Spetses, Greece
2011 Keynote Speaker, Australia and New Zealand Matrix Biology Society Meeting, Sydney, Australia
PEER REVIEW PARTICIPATION/STUDY SECTIONS
1986- Ad Hoc reviewer: Netherlands Cancer Foundation; Pathobiochemistry Study Section, NIH; Cell Biology Study Section, NIH; Pathology A, Study Section, NIH; Reviewer, Medical Research Council of Canada; Veterans Administration, National Science Foundation
1991 Member, Site Visit Team, National Heart and Lung and Blood Institute
1992 Ad hoc Reviewer, Pathobiochemistry Study Section, NIH
1993 Member, External Review Committee for the Department of Biochemistry, American Red Cross, Holland Laboratories, Rockville, MA
2000 Special Reviewer, Pathobiochemistry Study Section
2002- Member, NIH Special Emphasis Review Panel (ZRG1 BIO)
2003 Tumor Microenvironment Study Section, NIH
2006-08 Special Emphasis Panel Reviewer, NIHLB, NIH
2008 Member, External Review Panel for Molecular Biology Section, NIDCR, NIH
2009 Special Emphasis Panel/Scientific Review Group 2010/01 HLBP
2009 Special Emphasis Panel/Scientific Review Group 2010/01 ZRG1 OTC-D
2010- Member of the College of CSR Reviewers, NIH